MTHFR – could this test change your life?
It is estimated that up to 50 percent of the population has an inborn genetic mutation of the MTHFR gene, many of our clients whose health concerns have previously remained a mystery have found that the discovery of MTHFR and its affects on health have been life changing.
Many conditions relate to MTHFR gene mutations including:
o Chronic fatigue
o Addictions – smoking, drugs, alcohol
o Cardiovascular issues - high blood pressure, high cholesterol, stroke, heart attack, deep vein thrombosis
o Depression and anxiety
o Bipolar disorder
o Learning difficulties, difficulty concentrating, brain fog
o ADD or ADHD
o Chronic constipation and other gastrointestinal complaints
Testing for MTHFR is done through a simple and inexpensive blood or saliva test.
What is MTHFR?
MTHFR (MethylTetraHydroFolate Reductase) is a key enzyme required for methylation pathways in the body, including the metabolism of folate and homocysteine. This process of methylation is a simple one and is essential for life and health.
Certain genetic single nucleotide polymorphisms “SNP’s” or “snips” of the MTHFR gene affect folate metabolism and can be associated with high homocysteine levels in the body and impaired methylation.
Problems with methylation contribute to oxidative damage and carcinogenisis, fat metabolism, neurological and cardiovascular function.
The most common mutation in the MTHFR gene is called C677T. Individuals with two copies of this mutation (i.e. one inherited from their mother and one from their father) are called homozygotes. These individuals are predisposed to developing high levels of homocysteine particularly when their diets are low in folate.
A second mutation in the MTHFR gene, called A1298C, is also associated with health concerns and can be more of a problem when there are other methylation or cytochrome mutations present.
Treatment strategies differ for each mutation and from case to case.